Plan to spend 40 minutes on HWE

1. Consider a locus with two alleles, A and B. The frequency of allele A is 0.36. What are the frequencies of AA, AB and BB genotypes under Hardy-Weinberg equilibrium? Answer
2. Consider a locus with two alleles, A and B. The frequency of allele A is 0.16. What are the frequencies of AA, AB and BB genotypes under Hardy-Weinberg equilibrium?Answer
3. Consider a locus with 5 alleles (named from A_1 to A_5). The frequency of allele A_1 ... A_4 are 0.1666, 0.7158, 0.0473, 0.0616, respectively. What are the frequencies of A_1/A_1, A_1/A_2, ... A_5/A_5 genotypes under Hardy-Weinberg equilibrium?Answer
4. Two alleles are present in a locus with frequencies 0.3 and 0.7. Heterozygous genotype is difficult to call: it is called correctly in 80% of cases, in 10% of cases it is called as 11 and in 10% of cases it is called as 22. What will be observed genotypic distribution?