FREGAT home page

A new and improved version of FREGAT R package is now available on CRAN

FREGAT R package supplies the most common and efficient tests for the region-based association analysis aimed at identification of rare genetic variants for family-based, genetically related or population samples. Tests implemented are FFBSKAT (sequence kernel association test), FFBSKAT optimal, famBT (burden test), and famFLM (functional linear model, a functional data analysis approach).

If you use FREGAT in your work, please cite:
Belonogova N.M., Svishcheva, G.R. and Axenovich, T.I. (2016) FREGAT: an R package for region-based association analysis. Bioinformatics, doi: 10.1093/bioinformatics/btw160

FREGAT is a freeware for non-commercial use. It is distributed under GPLv3 license.

Please send your comments and bug reports to:
Nadezhda Belonogova (
Gulnara Svishcheva (
Last modified: 28 March 2016