famFLM: A region-based association test for familial data under functional linear models
A new and improved version of famFLM is now a part of the FREGAT R package available on CRAN The FREGAT package supplies the most common and efficient tests for the region-based association analysis aimed at identification of rare genetic variants for family-based, genetically related or population samples. Along with famFLM, burden tests, FFBSKAT and FFBSKAT optimal are implemented.
DOWNLOADS (Please use FREGAT package for newer version of famFLM() function!):
| famFLM R-function (with usage information inside): | |
| Example data: |
NOTE:
famFLM requires R packages 'GenABEL' (for null model estimation) and 'fda' (for functional basis estimation). To enable parallel calculation, packages 'foreach' and 'doSNOW' should be installed. To install R packages automatically from CRAN repositories, please use in R:
install.packages(c('GenABEL', 'fda', 'foreach', 'doSNOW'))
famFLM is a freeware for non-commercial use. It is distributed under GPLv3 license.
If you use famFLM in your work, please cite: Svishcheva, G.R., Belonogova, N.M. and Axenovich, T.I. (2015) Region-based association test for familial data under functional linear models. PLoS One, 10, e0128999.
| Please send your comments and bug reports to: | Gulnara Svishcheva (gulsvi@mail.ru) |
Nadezhda Belonogova (belon@bionet.nsc.ru) |